Medicinal Resources Chemistry
Academic staff:
- Associate Professor Michiharu Sugiura, Ph.D.
- Associate Professor Yoshiaki Takaya, Ph.D.
Research themes:
- Discovering medicinal resources through organic chemistry
- Discovering bioactive organic compounds and studying their structures
Drug Informatics
Academic staff:
- Professor Nobuyuki Goto, Ph.D.
- Associate Professor Fumiko Ohtsu, Ph.D.
Research themes:
- Researching the proper use of medicinal products
- Identifying risk factors, subjective symptoms, and healthcare economics related to the diagnosis of medicinal side effects
- Studying medicines and pharmaceuticals that can meet on-site clinical needs
- Developing a database for organizing information on medicinal side effects
Hygiene Chemistry
Academic staff:
- Professor Nakao Kojima, Ph.D.
- Assistant Professor Koji Ueda, Ph.D.
- Assistant Professor Yoshinori Okamoto, Ph.D.
Research themes:
- Studying the dynamics of environmental chemicals; how such chemicals interfere with the metabolism and the endocrine system; how their mutagenicity is expressed; and how they can be controlled
- Conducting studies related to food hygiene and environmental contamination
- Applying pluripotential stem cells to pharmaceutical health chemistry
Environmental Sciences
Academic staff:
- Professor Ken-ichi Harada, Ph.D.
- Associate Professor Hideaki Yamaguchi, Ph.D.
Research themes:
- Regulating cyanobacteria in aquatic ecosystems
- Decomposing environmental pollutants using microorganisms
- Deriving anticancer drugs from natural products, in line with ecosystem conservation (Yamaguchi)
- Conducting in silico structural analysis of protein-ligand interactions (Yamaguchi)
Functional Molecular Chemistry
Academic staff:
- Professor Osamu Hara, Ph.D.
- Assistant Professor Yasuhiro Nishikawa, Ph.D.
Research themes:
- Design and application of novel binuclear metal complexes with pyrazole for asymmetric reactions
- Development of highly chemoselective oxidation reactions utilizing C-H activation
- Development of methodologies applying cationic heteroaromatics for selective activation by electronic charge transfer
Industrial Pharmacy
Academic staff:
- Professor Toshiyuki Niwa, Ph.D.
- Assistant Professor Keita Kondo, Ph.D.
Research themes:
- Designing nanocrystals by conducting cryogenic grinding in liquid nitrogen
- Designing dry nano-suspensions
- Developing a new method for producing functional particle pharmaceuticals
Analytical Neurobiology
Academic staff:
- Professor Norio Kaneda, Ph.D.
- Associate Professor Tomiyasu Murata, Ph.D.
- Instructor Kiyomi Hikita, M.S.
Research themes:
- Conducting molecular-cell biological studies on the onset mechanism of neurodegenerative disease and cancer
- Studying the association of low-molecular-weight N-methyltransferase with Parkinson’s disease
- Studying the association of glyoxalase I with neurodegenerative disease and cancer
- Examining how the formation of stress granules is associated with intracellular stress-activated response
- Elucidating the onset mechanism of type 2 diabetes mellitus resulting from the failure of stress-activated response by pancreatic β cells
- Studying the intracellular signal transduction that controls adipocyte differentiation
Biophysical Chemistry
Academic staff:
- Associate Professor Eiji Kurimoto, Ph.D.
Research themes:
- Employing structural biology to study the ubiquitin-proteasome system
- Applying protein characteristics to various biosensors
Pharmacognosy
Academic staff:
- Professor Mitsuhiko Nose, Ph.D.
- Assistant Professor Shinsuke Hisaka, Ph.D.
Research themes:
- Performing scientific analysis of Chinese medicinal prescriptions
- Conducting functional analysis of oxidatively modified proteins and studying how they can be controlled by herbal medicines and food-derived factors
- Scientifically verifying conventional medical practice and medication and studying how they can be applied to drug discovery
- Empirically studying folk remedies and establishing their proper usage
Physiology
Academic staff:
- Professor Kazunori Yukawa, M.D. & Ph.D.
- Assistant Professor Kenji Yoshida, Ph.D.
- Assistant Professor Takayuki Negishi, D.V.M. & Ph.D.
Research themes:
- Studying a new action mechanism for the axon guidance molecule Semaphorin
- Researching a new action mechanism for the apoptosis-related molecule DAPK
- Examining the cause of diabetes insipidus observed among model rats with hereditary cataracts (ICR/f)
- Studying the onset mechanism of—and the treatment method for—type 1 diabetes mellitus
- Assessing the influence of environmental chemicals on developing brains
Natural Products Chemistry
Academic staff:
- Professor Hitoshi Tanaka, Ph.D.
Research theme:
- Studying biologically active substances present in tropical plants
Microbiology
Academic staff:
- Professor Toshiaki Nikai, Ph.D.
- Associate Professor Yumiko Komori, Ph.D.
- Associate Professor Keiichi Uchiya, Ph.D.
Research themes:
- Researching pathogenesis factors of Aspergillosis and inhibitors of those factors
- Conducting epidemiological studies on nontuberculous mycobacteria infection based on genetic analysis; identifying pathogenesis factors; and developing a gene-diagnostic method
- Analyzing the virulence gene of Salmonella
- Developing methods for evidence-based infection control
- Studying the structure and function of bioactive substances present in snake venom
Office of Clinical Pharmacy Practice and Health Care Management
Academic staff:
- Professor Hiroyuki Kamei, Ph.D.
- Associate Professor Manako Hanya, Ph.D.
- Assistant Professor Aiko Fukui
Research themes:
- Studying proper usage of medicinal products for psychiatric patients; analyzing pathology of mental disorders
- Studying interactions between pharmacists and patients
- Developing and establishing methods of pharmacotherapy
- Developing a methodology for promoting the education of clinical pharmacists
Pathobiochemistry
Academic staff:
- Professor Shuhei Yamada, Ph.D.
- Associate Professor Yukiyasu Toyoda, Ph.D.
- Assistant Professor Shuji Mizumoto, Ph.D.
Research themes:
- Functions, structure, biosynthesis, metabolism, and medical application of proteoglycans and glycosaminoglycans
- Biochemical studies on the enzymes responsible for the biosynthesis and metabolism of glycans aiming at their medical application
- Mechanism of hepatic glucose metabolism in mammals; development of preventives and remedies for diabetes mellitus and obesity
- Nutritional assessments of semi-solid enteral nutrients
Molecular Design and Synthesis
Academic staff:
- Professor Yuji Mori, Ph.D.
- Assistant Professor Takeo Sakai, Ph.D.
Research themes:
- Development of new synthetic reactions using oxiranyl anion as a nucleophilic epoxide
- Development of new strategies for the synthesis of oxygen-containing heterocyclic compounds
- Total synthesis of bioactive marine polycyclic ethers produced by toxic dinoflagellates
- Synthesis and application of new superacid anions
- Development of new Lewis acid catalysis characterized by electron-withdrawing cyclopentadienides
Medicinal Chemistry
Academic staff:
- Professor Shinji Kitagaki, Ph.D.
- Associate Professor Chihiro Ito, Ph.D.
- Assistant Professor Naoko Takenaga, Ph.D.
Research themes:
- Studying functional molecules based on a novel framework
- Developing multicomponent reactions and one-pot reactions toward the efficient synthesis of natural products
- Searching for novel anti-tumor substances and anti-tumor promoters in plant resources
- Researching seed compounds regarding the differentiation of ES and iPS cells
Analytical Pharmacology
Academic staff:
- Professor Tadashi Nagamatsu, Ph.D.
- Associate Professor Ryoji Kojima, Ph.D.
- Assistant Professor Tomohiro Mizuno, Ph.D.
Research themes:
- Studying the onset and progress mechanism of diabetic nephropathy
- Researching the structure and functions of a new molecular chaperone, Osp94, and cell cycle-related molecules
- Improving pharmacotherapy for treating patients suffering from renal failure
Pharmaceutics
Academic staff:
- Professor Masayuki Nadai, Ph.D.
- Associate Professor Miki Katoh, Ph.D.
Research themes:
- In vivo and in vitro pharmacokinetic analysis
- Research on the nature and mechanism of pharmacokinetic changes in pathological states
Chemical Pharmacology
Academic staff:
- Professor Masayuki Hiramatsu, Ph.D.
- Assistant Professor Takayoshi Mamiya, Ph.D.
Research themes:
- Elucidation of pathological mechanisms and prevention of dementia, and development of new therapeutic drugs
- Studying stress-mediated neuropsychiatric disorders
- Development of animal models and new therapies for stress-related diseases
- Elucidation of the mechanism underlying drug dependence (methamphetamine and nicotine)
Physical Pharmacy
Academic staff:
- Associate Professor Yorinobu Yonezawa, Ph.D.
Research themes:
- Analyzing the process of drug dissolution and elution from solid preparations
- Analyzing the process of drug release from matrix preparations
- Designing drug formulations with a focus on dissolution and elution
- Designing drug formulations with a focus on release mechanisms
Drug Delivery Research
Academic staff:
- Professor Hirokazu Okamoto, Ph.D.
- Assistant Professor Tomoyuki Okuda, Ph.D.
Research themes:
- Conducting studies related to the development of inhalants for gene delivery
- Studying a new method for formulating inhalants
- Studying the proper usage of inhalants
Clinical Medicine
Academic staff:
- Professor Tsutomu Yoshida, M.D. & Ph.D.
Research themes:
- Preventing and treating occupational respiratory disease
- Developing a methodology for educating and training clinical pharmacists
Clinical Economics
Academic staff:
- Professor Hiroyuki Sakamaki, MBA, Dr. Med. Sci.
Research themes:
- Researching government policies related to medicinal products; analyzing reimbursement of medical treatment and prescription from the standpoint of medical economics; investigating environmental factors surrounding pharmaceutical companies and pharmacists
- Assessing medical technology; analyzing cost effectiveness, medication-related aspects, and duties of pharmacists from the standpoint of medical economics; developing efficacy indicators